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It is forbidden for BMI160 to keep IO level as high but turn off the VDDIO.
Because of the internal registier, you will see this leak current and it is also potential to damage the sensor.
In order to keep BMI160 off and not affect the bus communicaiton, i suggest to turn off the VDD of BMI160 but still keep VDDIO of BMI160 as same level of IO pins.
BMI160 will be power down if VDD is off.