Hello Ricky,
You can't handle 2 BME680s together in BSEC.
But, you can handle it using BME68x API. https://github.com/BoschSensortec/BME680_driver
And, I think I2C issue could happen when you set same i2c address for 2 bme680 in one i2c communicattion.
You should set primary address for one bme680 and secondary address for the other.
Regarding setting address, you can check 6.2 i2c interface in datasheet.
https://www.bosch-sensortec.com/media/boschsensortec/downloads/datasheets/bst-bme680-ds001.pdf
Thanks,
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