Unfortunately some information is missing to understand your issue:
Can you confirm that your read/write transactions work fine? For examples, is the chip ID correct? Are temperature/pressure/humidity outputs relevant?
How are you using the snippet that you've shared? This code alone only triggers one measurements then the sensor goes back to standby mode. Unless it is called repeatably, outputs are not expected to change.
Without full ADC and trimming values, we cannot make sense of raw register values. If the sensor API is otherwise working, you could directly share raw gas values in ohms.
Are you using a BME680 shuttle board? Or a custom-made PCB?
Is the resistance value sometimes changing at all (for e.g. when your program starts running) then gets stuck after some time, or is it never changing at all?
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